TMA-DPH
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
TMA-DPH是一种用于测定人造和活体膜系统中膜流动性的荧光探针。该探针通常用于标记细胞膜双层和质膜的外小叶[1]，也可用于追踪质膜的胞吐作用和内吞作用。TMA-DPH是DPH的阳离子衍生物，DPH是疏水性分子，由于其亲脂性高，倾向于嵌入到双层膜中，通常用于标记双层的疏水性核心，相比之下，TMA-DPH包含阳离子三甲基铵取代基，其起表面锚定作用，固定在水/脂质界面中的膜表面上，TMA-DPH更适合研究膜的运动动力学。两者插入膜中会伴随荧光的强烈增强；它们在水中几乎不发荧光。TMA-DPH的光谱学相关参数为Ex=355nm / Em=430nm。
References:
[1] Chazotte B. Labeling the plasma membrane with TMA-DPH. Cold Spring Harb Protoc. 2011;2011(5):pdb.prot5622. Published 2011 May 1.
| Physical Appearance | A crystalline solid |
| Storage | Store at -20°C |
| M.Wt | 461.62 |
| Cas No. | 115534-33-3 |
| Formula | C28H31NO3S |
| Solubility | ≤1mg/ml in methanol;10mg/ml in DMSO;1mg/ml in dimethyl formamide |
| Chemical Name | N,N,N-trimethyl-4-((1E,3E,5E)-6-phenylhexa-1,3,5-trien-1-yl)benzenaminium 4-methylbenzenesulfonate |
| SDF | Download SDF |
| Canonical SMILES | C[N+](C)(C1=CC=C(C=C1)/C=C/C=C/C=C/C2=CC=CC=C2)C.CC3=CC=C(C=C3)S([O-])(=O)=O |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
