HDAC
Histone deacetylases (HDACs), known for their ability to target histones as well as more than 50 non-histone proteins, are classified into three major classes according to their homology to yeast proteins, including class I (HDAC1, HDAC2, HDAC3 and HDAC8), class II (HDAC4, HDAC5, HDAC7 and HDAC9) and class IV (HDAC11). HDAC inhibitors, a large group of compounds that is able to induce the accumulation of acetylated histones as well as non-histone proteins, are divided into several structural classes including hydroxamates, cyclic peptides, aliphatic acids and benzamides. HDAC inhibitors have been investigated for their efficacy as anticancer agents in the treatment of a wild range of cancers.
- C5334 BRD6688Summary: HDAC抑制剂
- C4018 4-iodo-SAHASummary: I类和II类组蛋白去乙酰化酶(HDAC)抑制剂
- B7816 ITSA-1 (ITSA1)Summary: HDAC激活剂,通过抑制Trichostatin A (TSA)
- B5969 2-hexyl-4-Pentynoic AcidSummary: HDAC抑制剂
- B5968 BML-210(CAY10433)Summary: HDAC抑制剂
- B5967 UF 010Summary: I类HDAC抑制剂
- B5949 BG45Summary: HDAC3抑制剂
- B5936 ACY-241Summary: HDAC6抑制剂
- B5916 Chidamide1 CitationTarget: HDACSummary: HDAC抑制剂
- B4890 HPOB1 CitationTarget: Histone Deacetylases (HDACs)Summary: HDAC6抑制剂