parathyroid hormone (7-34) [Homo sapiens]/[Macaca fascicularis]
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
甲状旁腺激素(7-34)化学式为C154H246N48O40S2,氨基酸序列H2N-LMHNLGKHLNSMERVEWLRKKLQDVHNF-OH,分子量为 3474.03。甲状旁腺激素(PTH),又称为甲状旁腺激素或甲状旁腺,是由甲状旁腺主细胞分泌的含有84个氨基酸的多肽。它的作用是增加血液中钙的浓度,PTH通过作用于甲状旁腺激素1受体和甲状旁腺激素2受体,增加血液中的钙浓度(1)。 PTH降低肾脏的近端小管磷酸盐的再吸收,这意味着更多的磷酸盐通过尿排出体外。PTH增加从肠道和骨头吸收进入血液的磷酸盐含量(2)。在骨中,从破碎的骨中释放的钙的含量比磷酸盐稍多。在肠内,活性维生素D增加,介导钙和磷的吸收。
Figure1 Formula of parathyroid hormone (7-34)
Figure2 structure of parathyroid hormone
参考文献:
1. Bieglmayer C, Prager G, Niederle B (October 2002). "Kinetic analyses of parathyroid hormone clearance as measured by three rapid immunoassays during parathyroidectomy". Clin. Chem. 48 (10): 1731–8.
2. PooleK, Reeve J (2005). "Parathyroid hormone - a bone anabolic and catabolic agent". Curr Opin Pharmacol 5 (6): 612–7.
Physical Appearance | A solid |
Storage | Store at -20°C |
M.Wt | 3474.03 |
Formula | C154H246N48O40S2 |
Synonyms | H2N-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-OH |
Solubility | ≥347.4 mg/mL in DMSO; ≥17.33 mg/mL in EtOH with ultrasonic; ≥77.2 mg/mL in H2O |
运输条件 | 蓝冰运输或根据您的需求运输。 |
一般建议 | 不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。 |
质量控制和MSDS
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