MK-8033
Catalog No.
A3624
C-MET抑制剂
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Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
MK-8033 is a c-MET inhibitor in clinical trials. MK8033 is a selective small-molecule inhibitor, ATP competitive. Phase I investigation of the cMet inhibitor MK-8033 is ongoing. Plans include a trial of this agent in refractory colorectal cancer, with pre- and post-treatment biopsies to evaluate for relevant molecular signatures.
Storage | Store at -20°C |
M.Wt | 471.53 |
Cas No. | 1001917-37-8 |
Formula | C25H21N5O3S |
Synonyms | MK 8033;MK8033 |
Solubility | Soluble in DMSO |
Chemical Name | 1-(3-(1-methyl-1H-pyrazol-4-yl)-5-oxo-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl)-N-(pyridin-2-ylmethyl)methanesulfonamide |
SDF | Download SDF |
Canonical SMILES | CN1C=C(C2=CN=C3C=CC4=C(C(C3=C2)=O)C=C(CS(=O)(NCC5=CC=CC=N5)=O)C=C4)C=N1 |
运输条件 | 蓝冰运输或根据您的需求运输。 |
一般建议 | 不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。 |
化学结构
![MK-8033](http://www.apexbt.com//media/diy/images/struct/A3624.png)