Cefoxitin (sodium salt)
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mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
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Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
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Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
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Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
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SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
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Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
Cefoxitin (sodium salt) is a second generation cephalosporin antibiotic that was used to treat a wide range of gram-negative and gram-positive bacteria [1][2].
Cefoxitin, 3-carbamoyloxymethyl-7-a-methoxy-7- [2-(2-thienyl)acetamido]-3-cephem-4-carboxylic acid, is a semisynthetic cephamycin antibiotic with broad-spectrum activity. Cefoxitin is also active in vivo against a wide variety of bacteria including penicillin-resistant staphylococci and effective against gram-negative organisms including strains of indole-positive Proteus [1].
In mice, cefoxitin was more active against the cephalosporin-sensitive gram-negative bacteria, strains of E.coli, indole-producing Proteus, and Serratia, and the lactamase producing 2646. Cefoxitin was degraded by the lactamase of E. cloacae at a much slower rate than are the cephalosporins. In pharmacological studies, cefoxitin was found in sera and detected in urine samples in amounts greater than those of cephalothin and less than those of cephaloridine [1].
References:
[1]. Miller AK, Celozzi E, Kong Y, et al. Cefoxitin, a semisynthetic cephamycin antibiotic: in vivo evaluation. Antimicrob Agents Chemother. 1974 Jan;5(1):33-7.
[2]. Jacoby GA. AmpC beta-lactamases. Clin Microbiol Rev.2009 Jan;22(1):161-82.
Storage | Store at -20°C |
M.Wt | 449.4 |
Cas No. | 33564-30-6 |
Formula | C16H16N3O7S2·Na |
Synonyms | Betacef,Cenomycin,Farmoxin,Mefoxin,Merxin |
Solubility | insoluble in EtOH; ≥12.9 mg/mL in DMSO; ≥54.8 mg/mL in H2O |
Chemical Name | (6R,7S)-3-[[(aminocarbonyl)oxy]methyl]-7-methoxy-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, monosodium salt |
SDF | Download SDF |
Canonical SMILES | O=C1[C@](NC(CC2=CC=CS2)=O)(OC)[C@]3([H])N1C(C([O-])=O)=C(COC(N)=O)CS3.[Na+] |
运输条件 | 蓝冰运输或根据您的需求运输。 |
一般建议 | 不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。 |
质量控制和MSDS
- 批次:
化学结构
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