DiscoveryProbe™ Apoptosis Compound Library
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
| Catalog No. | Product Name | Summary | Targets | CAS Number | Smiles | |
| A1902 | Z-VAD-FMK | Cell-permeable, irreversible pan-caspase inhibitor | Caspase | 187389-52-2 | CC(C)C(C(=O)NC(C)C(=O)NC(CC(=O)OC)C(=O)CF)NC(=O)OCC1=CC=CC=C1 | |
| A2005 | Nutlin-3b | MDM2/p53 inhibitor | MDM2 | 675576-97-3 | CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl | |
| A3762 | RG7112 | MDM2 inhibitor, first clinical | MDM2 | 939981-39-2 | CCOC1=C(C=CC(=C1)C(C)(C)C)C2=NC(C(N2C(=O)N3CCN(CC3)CCCS(=O)(=O)C)(C)C4=CC=C(C=C4)Cl)(C)C5=CC=C(C=C5)Cl | |
| A4213 | Necrostatin-1 | RIP1 inhibitor | TNF-α | 4311-88-0 | CN1C(=O)C(NC1=S)CC2=CNC3=CC=CC=C32 | |
| A4484 | PRIMA-1MET | Restore mutant p53 activity, induce BAX and PUMA | p53 | 5291-32-7 | COCC1(C(=O)C2CCN1CC2)CO | |
| A8177 | PAC-1 | Procaspase-3 activator | Caspase | 315183-21-2 | C=CCC1=CC=CC(=CNNC(=O)CN2CCN(CC2)CC3=CC=CC=C3)C1=O | |
| A8223 | CID 2011756 | PKD inhibitor | Protein Ser/Thr Phosphatases | 638156-11-3 | C1COCCN1CC2=CC=C(C=C2)NC(=O)C3=CC=C(O3)C4=CC(=CC=C4)Cl | |
| B3232 | Z-IETD-FMK | Caspase-8 inhibitor | Caspase | 210344-98-2 | CCC(C)C(C(=O)NC(CCC(=O)OC)C(=O)NC(C(C)O)C(=O)NC(CC(=O)OC)C(=O)CF)NC(=O)OCC1=CC=CC=C1 | |
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下载 APExBIO化合物库使用说明 下载 DiscoveryProbe™ Apoptosis Compound Library（SDF & XLSX） |
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相关生物数据
相关生物数据
相关生物数据
相关生物数据
相关生物数据
相关生物数据
" to show IC50| Form | Pre-dissolved DMSO solutions | Stability | Solution: -20°C for 12 months, -80°C for 24 months |
| Packaging | 96-well DeepWell format with peelable foil seal and EVA cap (100 μL/well, 10 mM DMSO). 96-well rack with Matrix 2D Barcoded ScrewTop Storage tubes (250 μL or 100 μL/well, 10 mM DMSO). |
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| Shipping Condition | Evaluation sample solution: ship with blue ice All other available size: ship with RT, or blue ice upon request |
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-- Available in stock with overnight delivery and free shipping over $500.
-- Cost-effective and competitive price to save your budget.
-- Potent, selective and cell-permeable in inhibiting or activating target molecules.
-- Diverse in chemical structure and route of administration (oral/i.m/i.v injection etc.)
-- Detailed files describing potency, selectivity and applications etc.
-- Supported by published data from top peer-reviewed journals.
-- Guaranteed high quality with NMR and HPLC validation.
